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Female To Male Transsexuals Have Higher Androgen Levels, Not PCOS
dans Non classé Lundi 07 avril 2008 02:47

Contrary to abovementioned gain knowledge of, female-to-male transsexuals perpetrate not savour a superior majority of polycystic ovary syndrome (PCOS), by the other hand they do have by a extended way higher androgen height, according to a tentative study tenet contained by favour of publication in the Journal of Clinical Endocrinology & Metabolism (JCEM).

PCOS be an endocrine mess beside a host of symptom linked to elfin bumpy cysts on the ovaries. It is speckled with the overproduction of mannish hormones in females. Until short snag, it have be postulate that the prevalence of PCOS in female-to-male transsexuals is higher than majority.

“Several studies have story a higher prevalence of PCOS in female-to-male transsexuals but the numbers of patients be small and ultrasound be impossible for diagnosis,” said Dr. Andreas Mueller of Erlangen University Hospital in Erlangen, Germany. “This is the most basic prospective endocrine evaluation of female-to-male transsexuals using up-to-date state-of-the-art pattern have a fiddle with on transvaginal ultrasonography for diagnose PCOS or hyperandrogenemia.” Researchers nearly new clinical, biochemical, and ultrasound criteria to diagnose PCOS in a jumble of 61 female-to-male transsexuals, using the realize diagnostic procedures describe in the National Institutes of Health 1990 and Rotterdam 2003 criteria. These grades were compare prospectively with those of 94 stout unselected controls.

According to the researchers, the higher androgen levels be would-be to be of ovarian embryo, though it may be in the red to undetected self-medication with androgens impulsive inclusion in the study.

The study will also measure any effects on complete cholesterol, low-density lipoprotein or “bad” cholesterol, triglycerides, high-density lipoprotein or “good” cholesterol, blood sugar levels and attraction for inflammation, such as C-reactive protein and interleukin-6.

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A fast production comprehension of this on a daily opinion has been published on-line and will occur in the April 2008 feature of JCEM, a publication of The Endocrine Society Endocrine Society 8401 Connecticut Ave., Ste 900 Chevy Chase, MD 20815 United States

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